|
KMID : 1041219990410030141
|
|
Journal of Sericultural and Entomological Science
1999 Volume.41 No. 3 p.141 ~ p.146
|
|
|
Effects of Silkworm Powder on Oxygen Radicals and Their Scavenger Enzymes in Serum of Rats
|
|
|
|
|
Abstract
|
|
|
|
This study was designed to investigate the effects of silkworm powder (SWP) on oxygen radicals and their scavenger enzymes in serum of rats. Sprague Dawley (SD) male rats (160±10 g) were fed experimental diets (SWP-200 and SWP-400 groups) added 200 and 400 mg/kg Bw/day for 6 weeks. Triglyceride (TG) levels were significantly inhibited (10% and 25%) in SWP-200 and SWP-400 groups, but there were no significant differences in total, LDL- and HDL- cholesterol levels in both SWP-200 and SWP-400 groups. Hydroxyl radical (´OH) formations resulted in a marked decreases (about 20% ) in both SWP-200 and SWP-400 groups compared with control group. Superoxide radical(O2-) and hydrogen peroxide formations resulted in a significant decreases in SWP-400 groups compared with control group.Lipid peroxide (LPO) and oxidized protein (>C=0 group) productions resulted in a significant decreases (about 10%) in SWP-200 and SWP-400 groups compared with control group. Superoxide dismutase (SOD) and catalase (CAT) activities were remarkably increased (10-25% and 40-50%) in SWP-200 and SWP-400 groups. Glutathione peroxidase (GSHPx) activities were significantly increased (about 10% ) in SWP-400 groups compared with control group. These results suggest that anti-aging effect of silkworm powder (SWP) may play a pivotal role in attenuating a various chronic degenerative diseases and age-related changes.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|